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pentobarbital will lower the extent or result of lefamulin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Stay clear of coadministration of lefamulin with potent or average CYP3A inducers Except the gain outweighs hazards. Keep track of for reduced efficacy.Check Closely (2)pentobarbital will reduce t